Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (956 aa)    
Predicted Functional Partners:
PSMD14
26S proteasome non-ATPase regulatory subunit 14.
   
 0.999
PSMD12
26S proteasome non-ATPase regulatory subunit 12.
   
 0.999
PSMD2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
0.999
PSMD3
26S proteasome non-ATPase regulatory subunit 3.
   
 0.998
PSMD11
26S proteasome non-ATPase regulatory subunit 11.
   
 0.998
PSMD6
26S proteasome non-ATPase regulatory subunit 6.
   
 0.998
PSMD7
26S proteasome non-ATPase regulatory subunit 7.
   
 0.997
PSMD4
26S proteasome non-ATPase regulatory subunit 4.
   
 0.997
PSMC1
26S protease regulatory subunit 4; Belongs to the AAA ATPase family.
   
 0.997
PSMC5
26S protease regulatory subunit 8; Belongs to the AAA ATPase family.
   
 0.996
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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