Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HEG1Protein HEG 1. (1812 aa)    
Predicted Functional Partners:
KRIT1
Krev interaction trapped protein 1.
    
 0.992
CCM2
Malcavernin.
      
 0.789
MUC1
Mucin-1.
   
 0.751
ADGB
Androglobin; Belongs to the peptidase C2 family.
    
 0.692
WDFY3
WD repeat and FYVE domain-containing protein 3.
    
 
 0.686
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 
 0.685
IQCA1
IQ motif containing with AAA domain 1.
   
 0.678
LOC110484475
Mucin-5B.
   
 0.677
ENSLSDP00000021980
annotation not available
   
 0.677
LMLN
Leishmanolysin-like peptidase.
    
 
 0.663
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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