| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CMPK1 | CMPK2 | ENSLSDP00000017841 | ENSLSDP00000017576 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | UMP-CMP kinase 2, mitochondrial. | 0.969 |
| CMPK1 | UCK2 | ENSLSDP00000017841 | ENSLSDP00000013215 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.946 |
| CMPK1 | UMPS | ENSLSDP00000017841 | ENSLSDP00000002123 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Uridine 5'-monophosphate synthase. | 0.956 |
| CMPK1 | UPRT | ENSLSDP00000017841 | ENSLSDP00000016746 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Uracil phosphoribosyltransferase. | 0.946 |
| CMPK2 | CMPK1 | ENSLSDP00000017576 | ENSLSDP00000017841 | UMP-CMP kinase 2, mitochondrial. | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.969 |
| CMPK2 | DHODH | ENSLSDP00000017576 | ENSLSDP00000000468 | UMP-CMP kinase 2, mitochondrial. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.497 |
| CMPK2 | UCK2 | ENSLSDP00000017576 | ENSLSDP00000013215 | UMP-CMP kinase 2, mitochondrial. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.915 |
| CMPK2 | UMPS | ENSLSDP00000017576 | ENSLSDP00000002123 | UMP-CMP kinase 2, mitochondrial. | Uridine 5'-monophosphate synthase. | 0.955 |
| CMPK2 | UPRT | ENSLSDP00000017576 | ENSLSDP00000016746 | UMP-CMP kinase 2, mitochondrial. | Uracil phosphoribosyltransferase. | 0.954 |
| DHODH | CMPK2 | ENSLSDP00000000468 | ENSLSDP00000017576 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | UMP-CMP kinase 2, mitochondrial. | 0.497 |
| DHODH | DPYD | ENSLSDP00000000468 | ENSLSDP00000015086 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.536 |
| DHODH | GOLT1A | ENSLSDP00000000468 | ENSLSDP00000012793 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Golgi transport 1A. | 0.895 |
| DHODH | GOLT1B | ENSLSDP00000000468 | ENSLSDP00000013099 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Vesicle transport protein GOT1B. | 0.895 |
| DHODH | UMPS | ENSLSDP00000000468 | ENSLSDP00000002123 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Uridine 5'-monophosphate synthase. | 0.998 |
| DHODH | UPP1 | ENSLSDP00000000468 | ENSLSDP00000022214 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.695 |
| DHODH | UPP2 | ENSLSDP00000000468 | ENSLSDP00000025965 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.695 |
| DHODH | UPRT | ENSLSDP00000000468 | ENSLSDP00000016746 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Uracil phosphoribosyltransferase. | 0.581 |
| DPYD | DHODH | ENSLSDP00000015086 | ENSLSDP00000000468 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.536 |
| DPYD | GOLT1A | ENSLSDP00000015086 | ENSLSDP00000012793 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Golgi transport 1A. | 0.895 |
| DPYD | GOLT1B | ENSLSDP00000015086 | ENSLSDP00000013099 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Vesicle transport protein GOT1B. | 0.895 |