ZNFX1 protein (Lonchura striata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ZNFX1

NFX1-type zinc finger-containing protein 1. (1969 aa)

Predicted Functional Partners:

NRDE2

0.647

ADAR

0.561

NFX1

0.556

DICER1

0.555

TENT4B

0.537

TENT4A

0.537

CMPK2

0.492

AGO2

0.483

AGO3

0.483

AGO1

0.483

Your Current Organism:

Lonchura striata

NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAR	AGO2	ENSLSDP00000023500	ENSLSDP00000001663	Double-stranded RNA-specific adenosine deaminase.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.424
ADAR	DICER1	ENSLSDP00000023500	ENSLSDP00000010672	Double-stranded RNA-specific adenosine deaminase.	Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily.	0.692
ADAR	ZNFX1	ENSLSDP00000023500	ENSLSDP00000002265	Double-stranded RNA-specific adenosine deaminase.	NFX1-type zinc finger-containing protein 1.	0.561
AGO1	AGO2	ENSLSDP00000020970	ENSLSDP00000001663	Protein argonaute-1; Belongs to the argonaute family.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.803
AGO1	DICER1	ENSLSDP00000020970	ENSLSDP00000010672	Protein argonaute-1; Belongs to the argonaute family.	Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily.	0.882
AGO1	ZNFX1	ENSLSDP00000020970	ENSLSDP00000002265	Protein argonaute-1; Belongs to the argonaute family.	NFX1-type zinc finger-containing protein 1.	0.483
AGO2	ADAR	ENSLSDP00000001663	ENSLSDP00000023500	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Double-stranded RNA-specific adenosine deaminase.	0.424
AGO2	AGO1	ENSLSDP00000001663	ENSLSDP00000020970	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Protein argonaute-1; Belongs to the argonaute family.	0.803
AGO2	AGO3	ENSLSDP00000001663	ENSLSDP00000020963	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	0.869
AGO2	DICER1	ENSLSDP00000001663	ENSLSDP00000010672	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily.	0.980
AGO2	ZNFX1	ENSLSDP00000001663	ENSLSDP00000002265	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	NFX1-type zinc finger-containing protein 1.	0.483
AGO3	AGO2	ENSLSDP00000020963	ENSLSDP00000001663	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.869
AGO3	DICER1	ENSLSDP00000020963	ENSLSDP00000010672	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily.	0.882
AGO3	ZNFX1	ENSLSDP00000020963	ENSLSDP00000002265	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	NFX1-type zinc finger-containing protein 1.	0.483
CMPK2	ZNFX1	ENSLSDP00000017576	ENSLSDP00000002265	UMP-CMP kinase 2, mitochondrial.	NFX1-type zinc finger-containing protein 1.	0.492
DICER1	ADAR	ENSLSDP00000010672	ENSLSDP00000023500	Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily.	Double-stranded RNA-specific adenosine deaminase.	0.692
DICER1	AGO1	ENSLSDP00000010672	ENSLSDP00000020970	Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily.	Protein argonaute-1; Belongs to the argonaute family.	0.882
DICER1	AGO2	ENSLSDP00000010672	ENSLSDP00000001663	Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.980
DICER1	AGO3	ENSLSDP00000010672	ENSLSDP00000020963	Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily.	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	0.882
DICER1	ZNFX1	ENSLSDP00000010672	ENSLSDP00000002265	Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily.	NFX1-type zinc finger-containing protein 1.	0.555