Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ZNFX1NFX1-type zinc finger-containing protein 1. (1969 aa)    
Predicted Functional Partners:
MAVS
Mitochondrial antiviral-signaling protein.
     
  0.900
NRDE2
Protein NRDE2.
      
 0.792
SYNCRIP
Heterogeneous nuclear ribonucleoprotein Q.
    
   0.718
HNRNPR
Heterogeneous nuclear ribonucleoprotein R.
    
   0.718
TENT4B
Non-canonical poly(A) RNA polymerase PAPD5.
    
 
 0.653
TENT4A
Non-canonical poly(A) RNA polymerase PAPD7.
    
 
 0.653
IFIH1
Interferon-induced helicase C domain-containing protein 1.
   
  
 0.633
AGO2
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
    
 
 0.626
AGO3
Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.
    
 
 0.626
AGO1
Protein argonaute-1; Belongs to the argonaute family.
    
 
 0.626
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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