Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (487 aa)    
Predicted Functional Partners:
TNIP2
TNFAIP3-interacting protein 2.
   
 0.994
NFKB1
Nuclear factor NF-kappa-B p105 subunit.
   
 0.993
MAP3K14
Mitogen-activated protein kinase kinase kinase 14.
    
0.992
MAP2K1
Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
  
 
0.971
MAP2K2
Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.
  
 
0.970
IKBKB
Inhibitor of nuclear factor kappa-B kinase subunit beta.
    
0.959
CHUK
Inhibitor of nuclear factor kappa-B kinase subunit alpha.
    
0.957
NFKB2
Nuclear factor NF-kappa-B p100 subunit.
   
 0.937
NFKBIA
NF-kappa-B inhibitor alpha.
   
 0.742
PDCD10
Programmed cell death protein 10.
   
 
 0.685
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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