Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RREB1Ras-responsive element-binding protein 1. (1695 aa)    
Predicted Functional Partners:
KDM1A
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 0.875
CTBP1
C-terminal-binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.825
CTBP2
C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.825
LOC110477357
C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.763
HOOK1
Protein Hook 1.
    
 0.734
RCOR1
REST corepressor 1.
    
 0.698
CHD1
Chromodomain-helicase-DNA-binding protein 1.
   
 0.694
NFE2L2
Nuclear factor erythroid 2-related factor 2.
      
 0.679
NFIA
Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
    
 
 0.678
PGR
Progesterone receptor.
    
 0.607
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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