PDE6H protein (Lonchura striata) - STRING interaction network

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Score

PDE6H

Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma. (85 aa)

Predicted Functional Partners:

GUK1

0.901

GMPS

0.900

HPRT1

0.900

APRT

0.900

ITPA

0.900

GMPR

0.900

PDE6C

0.751

KCNV2

0.668

NPR2

0.662

LOC110477391

0.657

Your Current Organism:

Lonchura striata

NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APRT	GMPR	ENSLSDP00000007602	ENSLSDP00000014773	Adenine phosphoribosyltransferase.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.933
APRT	GMPS	ENSLSDP00000007602	ENSLSDP00000001879	Adenine phosphoribosyltransferase.	GMP synthase [glutamine-hydrolyzing].	0.980
APRT	GUK1	ENSLSDP00000007602	ENSLSDP00000011484	Adenine phosphoribosyltransferase.	Guanylate kinase.	0.956
APRT	HPRT1	ENSLSDP00000007602	ENSLSDP00000007003	Adenine phosphoribosyltransferase.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.939
APRT	ITPA	ENSLSDP00000007602	ENSLSDP00000013002	Adenine phosphoribosyltransferase.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.987
APRT	PDE6C	ENSLSDP00000007602	ENSLSDP00000024101	Adenine phosphoribosyltransferase.	Phosphodiesterase.	0.903
APRT	PDE6H	ENSLSDP00000007602	ENSLSDP00000002548	Adenine phosphoribosyltransferase.	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma.	0.900
GMPR	APRT	ENSLSDP00000014773	ENSLSDP00000007602	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Adenine phosphoribosyltransferase.	0.933
GMPR	GMPS	ENSLSDP00000014773	ENSLSDP00000001879	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	GMP synthase [glutamine-hydrolyzing].	0.987
GMPR	GUK1	ENSLSDP00000014773	ENSLSDP00000011484	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Guanylate kinase.	0.918
GMPR	HPRT1	ENSLSDP00000014773	ENSLSDP00000007003	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.932
GMPR	ITPA	ENSLSDP00000014773	ENSLSDP00000013002	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.941
GMPR	PDE6C	ENSLSDP00000014773	ENSLSDP00000024101	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Phosphodiesterase.	0.907
GMPR	PDE6H	ENSLSDP00000014773	ENSLSDP00000002548	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma.	0.900
GMPS	APRT	ENSLSDP00000001879	ENSLSDP00000007602	GMP synthase [glutamine-hydrolyzing].	Adenine phosphoribosyltransferase.	0.980
GMPS	GMPR	ENSLSDP00000001879	ENSLSDP00000014773	GMP synthase [glutamine-hydrolyzing].	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.987
GMPS	GUK1	ENSLSDP00000001879	ENSLSDP00000011484	GMP synthase [glutamine-hydrolyzing].	Guanylate kinase.	0.976
GMPS	HPRT1	ENSLSDP00000001879	ENSLSDP00000007003	GMP synthase [glutamine-hydrolyzing].	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.955
GMPS	ITPA	ENSLSDP00000001879	ENSLSDP00000013002	GMP synthase [glutamine-hydrolyzing].	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.965
GMPS	PDE6C	ENSLSDP00000001879	ENSLSDP00000024101	GMP synthase [glutamine-hydrolyzing].	Phosphodiesterase.	0.900