STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2AC1Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (129 aa)    
Predicted Functional Partners:
MYSM1
Histone H2A deubiquitinase MYSM1.
    
 0.975
AIFM1
Apoptosis-inducing factor 1, mitochondrial.
    
  0.901
PPIA
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
  0.900
LOC110483163
Histone H2B; Belongs to the histone H2B family.
 
 0.779
LOC110476495
Histone H2B 1/2/3/4/6; Belongs to the histone H2B family.
 
 0.779
LOC110483171
Histone H2B; Belongs to the histone H2B family.
 
 0.776
LOC110483172
Histone H2B; Belongs to the histone H2B family.
 
 0.775
LOC110467620
Histone H2B; Belongs to the histone H2B family.
 
 0.764
H2BE1
H2B.E variant histone 1.
  
 0.763
KDM6A
Lysine-specific demethylase 6A.
    
 0.723
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.