| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COMT | CYP1B1 | ENSLSDP00000018589 | ENSLSDP00000020041 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Cytochrome P450 1B1; Belongs to the cytochrome P450 family. | 0.955 |
| COMT | DBH | ENSLSDP00000018589 | ENSLSDP00000003515 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Dopamine beta-hydroxylase. | 0.957 |
| COMT | DDC | ENSLSDP00000018589 | ENSLSDP00000022189 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Aromatic-L-amino-acid decarboxylase. | 0.957 |
| COMT | LOC110471710 | ENSLSDP00000018589 | ENSLSDP00000006699 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | UDP-glucuronosyltransferase 2A2 isoform X1. | 0.913 |
| COMT | LOC110473115 | ENSLSDP00000018589 | ENSLSDP00000002650 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Transmembrane O-methyltransferase. | 0.943 |
| COMT | LOC110474872 | ENSLSDP00000018589 | ENSLSDP00000008987 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Amine oxidase. | 0.959 |
| COMT | LOC110474874 | ENSLSDP00000018589 | ENSLSDP00000009003 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Amine oxidase. | 0.962 |
| COMT | LOC110475456 | ENSLSDP00000018589 | ENSLSDP00000009246 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | UDP-glucuronosyltransferase 1-6. | 0.913 |
| COMT | LOC110485004 | ENSLSDP00000018589 | ENSLSDP00000006403 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Aldehyde dehydrogenase family 3 member B1. | 0.925 |
| COMT | PNMT | ENSLSDP00000018589 | ENSLSDP00000010314 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | Phenylethanolamine N-methyltransferase. | 0.948 |
| CYP1B1 | COMT | ENSLSDP00000020041 | ENSLSDP00000018589 | Cytochrome P450 1B1; Belongs to the cytochrome P450 family. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | 0.955 |
| CYP1B1 | LOC110471710 | ENSLSDP00000020041 | ENSLSDP00000006699 | Cytochrome P450 1B1; Belongs to the cytochrome P450 family. | UDP-glucuronosyltransferase 2A2 isoform X1. | 0.940 |
| CYP1B1 | LOC110473115 | ENSLSDP00000020041 | ENSLSDP00000002650 | Cytochrome P450 1B1; Belongs to the cytochrome P450 family. | Transmembrane O-methyltransferase. | 0.967 |
| CYP1B1 | LOC110475456 | ENSLSDP00000020041 | ENSLSDP00000009246 | Cytochrome P450 1B1; Belongs to the cytochrome P450 family. | UDP-glucuronosyltransferase 1-6. | 0.940 |
| DBH | COMT | ENSLSDP00000003515 | ENSLSDP00000018589 | Dopamine beta-hydroxylase. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. | 0.957 |
| DBH | DDC | ENSLSDP00000003515 | ENSLSDP00000022189 | Dopamine beta-hydroxylase. | Aromatic-L-amino-acid decarboxylase. | 0.965 |
| DBH | LOC110473115 | ENSLSDP00000003515 | ENSLSDP00000002650 | Dopamine beta-hydroxylase. | Transmembrane O-methyltransferase. | 0.938 |
| DBH | LOC110474872 | ENSLSDP00000003515 | ENSLSDP00000008987 | Dopamine beta-hydroxylase. | Amine oxidase. | 0.943 |
| DBH | LOC110474874 | ENSLSDP00000003515 | ENSLSDP00000009003 | Dopamine beta-hydroxylase. | Amine oxidase. | 0.943 |
| DBH | PNMT | ENSLSDP00000003515 | ENSLSDP00000010314 | Dopamine beta-hydroxylase. | Phenylethanolamine N-methyltransferase. | 0.985 |