Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HIST1H1BHistone H1.5. (137 aa)    
Predicted Functional Partners:
CDK1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.551
CCNE1
G1/S-specific cyclin-E1; Belongs to the cyclin family.
    
   0.503
HMGB2
High mobility group protein B2.
   
 0.444
CDK2
Cyclin dependent kinase 2.
   
 0.437
CDK3
Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily.
   
 0.437
CCNA1
Cyclin-A1; Belongs to the cyclin family.
   
 
 0.426
HMGB1
High mobility group protein B1.
    
 0.426
CCNA2
Cyclin-A2; Belongs to the cyclin family.
   
 
 0.415
LOC110478279
Histone H2A; Belongs to the histone H2A family.
   
 
 0.414
H2AZ1
Histone H2A; Belongs to the histone H2A family.
   
 
 0.414
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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