| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AK3 | CMPK2 | ENSLSDP00000019070 | ENSLSDP00000017576 | GTP:AMP phosphotransferase AK3, mitochondrial; Belongs to the adenylate kinase family. | UMP-CMP kinase 2, mitochondrial. | 0.488 |
| AK3 | DTYMK | ENSLSDP00000019070 | ENSLSDP00000000551 | GTP:AMP phosphotransferase AK3, mitochondrial; Belongs to the adenylate kinase family. | Thymidylate kinase. | 0.440 |
| AK3 | ENTPD6 | ENSLSDP00000019070 | ENSLSDP00000022507 | GTP:AMP phosphotransferase AK3, mitochondrial; Belongs to the adenylate kinase family. | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. | 0.613 |
| AK3 | LOC110482680 | ENSLSDP00000019070 | ENSLSDP00000008814 | GTP:AMP phosphotransferase AK3, mitochondrial; Belongs to the adenylate kinase family. | Nucleoside diphosphate kinase. | 0.965 |
| AK3 | NME3 | ENSLSDP00000019070 | ENSLSDP00000002687 | GTP:AMP phosphotransferase AK3, mitochondrial; Belongs to the adenylate kinase family. | Nucleoside diphosphate kinase. | 0.967 |
| AK3 | RRM1 | ENSLSDP00000019070 | ENSLSDP00000012244 | GTP:AMP phosphotransferase AK3, mitochondrial; Belongs to the adenylate kinase family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.970 |
| AK3 | RRM2B | ENSLSDP00000019070 | ENSLSDP00000025662 | GTP:AMP phosphotransferase AK3, mitochondrial; Belongs to the adenylate kinase family. | Ribonucleoside-diphosphate reductase subunit M2 B. | 0.942 |
| CMPK2 | AK3 | ENSLSDP00000017576 | ENSLSDP00000019070 | UMP-CMP kinase 2, mitochondrial. | GTP:AMP phosphotransferase AK3, mitochondrial; Belongs to the adenylate kinase family. | 0.488 |
| CMPK2 | DTYMK | ENSLSDP00000017576 | ENSLSDP00000000551 | UMP-CMP kinase 2, mitochondrial. | Thymidylate kinase. | 0.689 |
| CMPK2 | ENTPD6 | ENSLSDP00000017576 | ENSLSDP00000022507 | UMP-CMP kinase 2, mitochondrial. | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. | 0.900 |
| CMPK2 | LOC110482680 | ENSLSDP00000017576 | ENSLSDP00000008814 | UMP-CMP kinase 2, mitochondrial. | Nucleoside diphosphate kinase. | 0.964 |
| CMPK2 | NME3 | ENSLSDP00000017576 | ENSLSDP00000002687 | UMP-CMP kinase 2, mitochondrial. | Nucleoside diphosphate kinase. | 0.945 |
| CMPK2 | RRM1 | ENSLSDP00000017576 | ENSLSDP00000012244 | UMP-CMP kinase 2, mitochondrial. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.950 |
| CMPK2 | RRM2B | ENSLSDP00000017576 | ENSLSDP00000025662 | UMP-CMP kinase 2, mitochondrial. | Ribonucleoside-diphosphate reductase subunit M2 B. | 0.912 |
| CTPS1 | CTPS2 | ENSLSDP00000020643 | ENSLSDP00000001007 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.901 |
| CTPS1 | ITPA | ENSLSDP00000020643 | ENSLSDP00000013002 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.607 |
| CTPS1 | LOC110482680 | ENSLSDP00000020643 | ENSLSDP00000008814 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Nucleoside diphosphate kinase. | 0.944 |
| CTPS1 | NME3 | ENSLSDP00000020643 | ENSLSDP00000002687 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Nucleoside diphosphate kinase. | 0.944 |
| CTPS2 | CTPS1 | ENSLSDP00000001007 | ENSLSDP00000020643 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | 0.901 |
| CTPS2 | ITPA | ENSLSDP00000001007 | ENSLSDP00000013002 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.607 |