STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GUCY2CGuanylate cyclase. (1068 aa)    
Predicted Functional Partners:
RLOC_00004118
Uncharacterized protein.
   
 
 0.867
NPPC
Natriuretic peptide C.
    
 0.772
GAK
Cyclin-G-associated kinase.
      
 0.579
GTF3C6
General transcription factor 3C polypeptide 6.
      
 0.577
PDZD3
Na(+)/H(+) exchange regulatory cofactor NHE-RF4.
    
 
 0.574
NPPB
Natriuretic peptides A.
    
 0.543
GUCA1A
Guanylyl cyclase-activating protein 1.
    
 0.508
PDE6C
Phosphodiesterase.
   
 0.494
PDE6B
Phosphodiesterase.
   
 0.488
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
      
 0.448
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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