Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RHOT2Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (618 aa)    
Predicted Functional Partners:
MFN1
Mitofusin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 0.969
MFN2
Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 0.966
TOMM70
Mitochondrial import receptor subunit TOM70.
   
 0.962
USP30
Ubiquitin carboxyl-terminal hydrolase.
     
 0.955
PRKN
E3 ubiquitin-protein ligase parkin.
    
 0.938
MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1.
     
 0.931
FKBP8
Peptidylprolyl isomerase.
   
 0.930
LOC110477411
Mitochondrial ubiquitin ligase activator of nfkb 1-A.
     
 0.929
MARCHF5
E3 ubiquitin-protein ligase MARCH5.
    
 0.912
TAX1BP1
Tax1-binding protein 1.
    
 0.909
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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