Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)    
Predicted Functional Partners:
LIMK2
LIM domain kinase 2.
   
 0.990
LIMK1
LIM domain kinase 1.
   
 0.983
SSH2
Protein phosphatase Slingshot 2.
    
 0.981
SSH3
Protein phosphatase Slingshot 3.
    
 0.972
SSH1
Protein phosphatase Slingshot 1.
    
 0.972
ACTG1
Actin, cytoplasmic 2.
   
 0.968
ACTB
Actin, cytoplasmic 1.
   
 0.968
LOC110479753
Actin, cytoplasmic type 5.
   
 0.968
DSTN
Destrin; Belongs to the actin-binding proteins ADF family.
   
   0.917
WDR1
WD repeat-containing protein 1.
   
 
 0.910
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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