Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMPHAmphiphysin. (679 aa)    
Predicted Functional Partners:
BIN1
Myc box-dependent-interacting protein 1.
     
 
0.900
MAPT
Microtubule associated protein tau.
    
 
 0.774
BIN2
Bridging integrator 2-like.
    
 
 0.773
SYNJ1
Synaptojanin-1.
   
 
 0.771
MYC
Myc proto-oncogene protein.
    
 
 0.757
AP2A2
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
 
 0.755
AP2S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 
 0.744
WASL
Neural Wiskott-Aldrich syndrome protein.
   
 
 0.690
ENSLSDP00000021568
annotation not available
   
 
 0.689
RIN3
Ras and Rab interactor 3.
   
 
 0.689
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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