STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC110483129Cytochrome P450 2D3; Belongs to the cytochrome P450 family. (507 aa)    
Predicted Functional Partners:
CYP7A1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
  
 
 0.939
LOC110480744
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase.
   
 0.919
CYP17A1
Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.
  
 
0.910
STS
Steryl-sulfatase.
     
  0.900
LOC110469854
Cytochrome P450 4B1.
  
 0.576
LOC110481576
Cytochrome P450 3A40; Belongs to the cytochrome P450 family.
  
0.491
LOC110481678
Cytochrome P450 3A13.
  
0.487
AASDH
Acyl-CoA synthetase family member 4.
  
 0.459
NBN
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
    
 0.439
WRN
Werner syndrome ATP-dependent helicase.
    
 0.424
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.