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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ENTPD5Ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. (428 aa)    
Predicted Functional Partners:
CMPK1
UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
   
 
 0.956
ADSS1
Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
     
 0.943
ITPA
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
     
 0.939
AMPD3
AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
   
 
 0.939
NME3
Nucleoside diphosphate kinase.
     
 0.931
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1.
   
 
 0.930
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.
   
 
 0.930
AMPD1
AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
   
 
 0.928
LOC110472232
Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family.
  
 
0.927
ENTPD3
Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.
  
 
0.926
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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