Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISCA2Iron-sulfur cluster assembly 2, mitochondrial. (178 aa)    
Predicted Functional Partners:
ISCA1
Iron-sulfur cluster assembly 1, mitochondrial.
  
 0.996
IBA57
Putative transferase CAF17, mitochondrial.
  
 
 0.982
GLRX5
Glutaredoxin-related protein 5, mitochondrial.
   
 0.971
ISCU
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
  
 
 0.934
NFU1
NFU1 iron-sulfur cluster scaffold, mitochondrial.
  
 
 0.881
NFS1
Cysteine desulfurase, mitochondrial.
  
 
 0.879
LYRM4
LYR motif-containing protein 4; Belongs to the complex I LYR family.
   
 
 0.797
SCLY
Selenocysteine lyase.
  
 
 0.789
GLRX3
Glutaredoxin-3.
  
 0.783
HSCB
Iron-sulfur cluster co-chaperone protein HscB, mitochondrial.
   
 
 0.768
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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