Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
INSYN1UPF0583 protein C15orf59. (274 aa)    
Predicted Functional Partners:
IQSEC3
IQ motif and SEC7 domain-containing protein 3.
      
 0.704
BLOC1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]
    
   0.666
PROSER1
Proline and serine-rich protein 1.
      
 0.566
TMEM205
Transmembrane protein 205.
      
 0.566
METTL11B
Alpha N-terminal protein methyltransferase 1B.
      
 0.536
PIGZ
Mannosyltransferase.
      
 0.535
INSYN2A
Protein FAM196A.
      
 0.481
CUEDC1
CUE domain-containing protein 1.
   
  
 0.459
GLG1
Golgi apparatus protein 1.
      
 0.454
RIPK4
Receptor-interacting serine/threonine-protein kinase 4.
      
 0.452
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (16%) [HD]