Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NPC2Epididymal secretory protein E1. (150 aa)    
Predicted Functional Partners:
NPC1
Niemann-Pick C1 protein.
   
 0.990
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 0.907
SCAP
Sterol regulatory element-binding protein cleavage-activating protein.
   
 0.741
NUDT19
Nucleoside diphosphate-linked moiety X motif 19, mitochondrial.
    
   0.732
STARD3NL
MLN64 N-terminal domain.
      
 0.659
HACD3
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
      
 0.575
CHMP7
Charged multivesicular body protein 7.
      
 0.569
GM2A
Ganglioside GM2 activator.
   
  
 0.569
STARD3-2
StAR-related lipid transfer protein 3.
      
 0.568
STARD3
StAR-related lipid transfer protein 3.
      
 0.568
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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