Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RND3Rho-related GTP-binding protein RhoE. (244 aa)    
Predicted Functional Partners:
ROCK1
Rho-associated protein kinase 1.
    
 0.966
ARHGAP35
Rho GTPase-activating protein 35.
    
 0.878
ITSN2
Intersectin-2.
    
 0.846
PLXNB1
Plexin-B1.
    
 0.839
PLXNB2
Plexin-B2.
    
 0.839
KCTD10
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3.
    
 0.836
ENSLSDP00000023671
annotation not available
    
 0.826
ANLN
Actin-binding protein anillin.
    
 0.807
ROCK2
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 0.796
PLEKHG5
Pleckstrin y domain-containing family G member 5.
    
 0.763
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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