Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ZNF217Zinc finger protein 217. (1071 aa)    
Predicted Functional Partners:
KDM1A
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 0.973
RCOR1
REST corepressor 1.
    
 0.958
CTBP1
C-terminal-binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.780
CTBP2
C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.780
RCOR3
REST corepressor 3.
    
 0.741
NR5A2
Nuclear receptor subfamily 5 group A member 2.
    
  0.722
NR5A1
Steroidogenic factor 1.
    
  0.722
LOC110477357
C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.709
NRIP1
Nuclear receptor-interacting protein 1.
      
 0.678
NCOA3
Nuclear receptor coactivator 3.
   
 0.641
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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