Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PGFPlacental growth factor. (136 aa)    
Predicted Functional Partners:
ENG
Endoglin.
      
 0.873
VEGFC
Vascular endothelial growth factor C/D.
     
 0.822
FLT1
Vascular endothelial growth factor receptor 1.
    
 0.792
LOC110467886
Vascular endothelial growth factor receptor kdr-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.792
KDR
Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.737
FLT4
Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.725
FOS
Proto-oncogene c-Fos.
      
 0.591
TEK
Angiopoietin-1 receptor.
    
 0.565
ANGPT2
Angiopoietin-2.
      
 0.530
PDGFC
Platelet-derived growth factor C.
      
 0.523
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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