Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ERG28Putative ergosterol biosynthetic protein 28. (140 aa)    
Predicted Functional Partners:
CYP51A1
Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family.
   
 
 0.964
HSD17B7
3-keto-steroid reductase.
   
 
 0.928
SC5D
Lathosterol oxidase; Belongs to the sterol desaturase family.
   
 
 0.926
SIGMAR1
Sigma non-opioid intracellular receptor 1 isoform X1.
   
 
 0.925
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
    
 
 0.922
FDFT1
Squalene synthase.
   
 
 0.919
DHCR7
7-dehydrocholesterol reductase.
   
 
 0.844
LBR
Lamin-B receptor.
   
 
 0.844
FAXDC2
Fatty acid hydroxylase domain-containing protein 2; Belongs to the sterol desaturase family.
   
 
 0.768
MSMO1
Methylsterol monooxygenase 1; Belongs to the sterol desaturase family.
   
 
 0.768
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (20%) [HD]