Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OLIG3Oligodendrocyte transcription factor 3. (273 aa)    
Predicted Functional Partners:
NKX2-2
Homeobox protein Nkx-2.2.
   
 0.647
SOX8
Transcription factor SOX-8.
   
 
 0.646
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
 
 0.618
MBP
Myelin basic protein.
   
  
 0.585
PAX6
Paired box protein Pax-6.
   
 
 0.583
CNP
2',3'-cyclic-nucleotide 3'-phosphodiesterase.
      
 0.567
TANA
Tanabin; Belongs to the intermediate filament family.
      
 0.567
PDGFRA
Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
    
 
 0.565
SOX10
Transcription factor SOX-10.
   
 
 0.559
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.529
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.