Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
P4HBProtein disulfide-isomerase. (514 aa)    
Predicted Functional Partners:
ERO1A
ERO1-like protein alpha.
   
 0.989
ERO1B
ERO1-like protein beta.
   
 0.986
CALR
Calreticulin.
   
 0.937
HSPA5
Glucose-regulated protein; Belongs to the heat shock protein 70 family.
   
 0.934
P4HA2
Prolyl 4-hydroxylase subunit alpha-2.
   
 0.886
HSP90B1
Endoplasmin.
   
 0.884
MTTP
Microsomal triglyceride transfer protein large subunit.
    
 0.880
PDIA3
Protein disulfide-isomerase.
   
   0.853
P4HA1
Prolyl 4-hydroxylase subunit alpha-1.
   
 0.803
ENSLSDP00000001731
annotation not available
   
 0.763
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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