| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADHFE1 | AGXT | ENSLSDP00000020028 | ENSLSDP00000011951 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial. | Serine--pyruvate aminotransferase. | 0.882 |
| ADHFE1 | ALDH18A1 | ENSLSDP00000020028 | ENSLSDP00000020163 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.632 |
| ADHFE1 | LOC110472466 | ENSLSDP00000020028 | ENSLSDP00000003918 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial. | Putative low-specificity L-threonine aldolase 1. | 0.888 |
| ADHFE1 | MTHFR | ENSLSDP00000020028 | ENSLSDP00000012272 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.496 |
| AGXT | ADHFE1 | ENSLSDP00000011951 | ENSLSDP00000020028 | Serine--pyruvate aminotransferase. | Hydroxyacid-oxoacid transhydrogenase, mitochondrial. | 0.882 |
| AGXT | ALDH18A1 | ENSLSDP00000011951 | ENSLSDP00000020163 | Serine--pyruvate aminotransferase. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.451 |
| AGXT | GLDC | ENSLSDP00000011951 | ENSLSDP00000018945 | Serine--pyruvate aminotransferase. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.698 |
| AGXT | LOC110472466 | ENSLSDP00000011951 | ENSLSDP00000003918 | Serine--pyruvate aminotransferase. | Putative low-specificity L-threonine aldolase 1. | 0.945 |
| AGXT | PSPH | ENSLSDP00000011951 | ENSLSDP00000016748 | Serine--pyruvate aminotransferase. | Phosphoserine phosphatase. | 0.929 |
| ALDH18A1 | ADHFE1 | ENSLSDP00000020163 | ENSLSDP00000020028 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Hydroxyacid-oxoacid transhydrogenase, mitochondrial. | 0.632 |
| ALDH18A1 | AGXT | ENSLSDP00000020163 | ENSLSDP00000011951 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Serine--pyruvate aminotransferase. | 0.451 |
| ALDH18A1 | DLD | ENSLSDP00000020163 | ENSLSDP00000020398 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Dihydrolipoyl dehydrogenase. | 0.692 |
| ALDH18A1 | FPGS | ENSLSDP00000020163 | ENSLSDP00000000904 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.731 |
| ALDH18A1 | GLDC | ENSLSDP00000020163 | ENSLSDP00000018945 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.672 |
| ALDH18A1 | LOC110470132 | ENSLSDP00000020163 | ENSLSDP00000025821 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2. | 0.811 |
| ALDH18A1 | LOC110472466 | ENSLSDP00000020163 | ENSLSDP00000003918 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Putative low-specificity L-threonine aldolase 1. | 0.738 |
| ALDH18A1 | MTHFD2 | ENSLSDP00000020163 | ENSLSDP00000015670 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial. | 0.811 |
| ALDH18A1 | MTHFR | ENSLSDP00000020163 | ENSLSDP00000012272 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.678 |
| ALDH18A1 | PSPH | ENSLSDP00000020163 | ENSLSDP00000016748 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Phosphoserine phosphatase. | 0.719 |
| DLD | ALDH18A1 | ENSLSDP00000020398 | ENSLSDP00000020163 | Dihydrolipoyl dehydrogenase. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.692 |