STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOCS3Suppressor of cytokine signaling 3. (209 aa)    
Predicted Functional Partners:
JAK2
Tyrosine-protein kinase.
   
 0.985
TYK2-2
Tyrosine-protein kinase.
   
 0.972
JAK1
Tyrosine-protein kinase JAK1.
   
 0.972
LEPR
Leptin receptor.
    
 0.966
STAT1
Signal transducer and activator of transcription.
   
 0.964
STAT2
Signal transducer and activator of transcription.
   
 0.964
SOCS1
Suppressor of cytokine signaling 1.
   
 
0.948
INSR
Tyrosine-protein kinase receptor.
    
 0.924
CSF3R
Granulocyte colony-stimulating factor receptor.
   
 0.920
IRS4
Insulin receptor substrate 2-A.
    
 0.917
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: medium (80%) [HD]