STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1216 aa)    
Predicted Functional Partners:
GNAS
Guanine nucleotide-binding protein G(S) subunit alpha.
   
 0.973
GNAI3
Guanine nucleotide-binding protein G(K) subunit alpha.
   
 0.934
GNAI2
Guanine nucleotide-binding protein G(I) subunit alpha-2.
   
 0.934
LOC110469766
Guanine nucleotide-binding protein G(I) subunit alpha-1.
   
 0.934
PRKACB
cAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily.
    
 0.927
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 
 0.922
NTPCR
Cancer-related nucleoside-triphosphatase.
     
 0.909
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1.
     
 0.908
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3.
     
 0.908
PKM
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.902
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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