STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VIPAS39Spermatogenesis-defective protein 39. (491 aa)    
Predicted Functional Partners:
VPS33B
Vacuolar protein sorting-associated protein 33B; Belongs to the STXBP/unc-18/SEC1 family.
   
 
 0.957
VPS33A
Vacuolar protein sorting-associated protein 33A; Belongs to the STXBP/unc-18/SEC1 family.
   
 
 0.880
VPS16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
   
  
 0.711
RAB11FIP5
Rab11 family-interacting protein 5.
   
  
 0.596
VPS45
Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family.
   
  
 0.592
VPS39
Vam6/Vps39-like protein.
   
 
 0.585
VPS11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
   
  
 0.580
VPS18
Vacuolar protein sorting-associated protein 18.
      
 0.550
PRDM4
PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation.
      
 0.479
TMEM186
Transmembrane protein 186.
      
 0.461
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.