| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADSS1 | ADSS2 | ENSLSDP00000024021 | ENSLSDP00000014128 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.901 |
| ADSS1 | ASL | ENSLSDP00000024021 | ENSLSDP00000017484 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Argininosuccinate lyase. | 0.552 |
| ADSS1 | ASNS | ENSLSDP00000024021 | ENSLSDP00000024994 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Asparagine synthetase [glutamine-hydrolyzing]. | 0.929 |
| ADSS1 | ASS1 | ENSLSDP00000024021 | ENSLSDP00000004246 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Argininosuccinate synthase. | 0.949 |
| ADSS1 | CPS1 | ENSLSDP00000024021 | ENSLSDP00000001898 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Carbamoyl-phosphate synthase [ammonia], mitochondrial. | 0.433 |
| ADSS1 | ENSLSDP00000001775 | ENSLSDP00000024021 | ENSLSDP00000001775 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | annotation not available | 0.552 |
| ADSS2 | ADSS1 | ENSLSDP00000014128 | ENSLSDP00000024021 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.901 |
| ADSS2 | ASL | ENSLSDP00000014128 | ENSLSDP00000017484 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Argininosuccinate lyase. | 0.552 |
| ADSS2 | ASNS | ENSLSDP00000014128 | ENSLSDP00000024994 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Asparagine synthetase [glutamine-hydrolyzing]. | 0.929 |
| ADSS2 | ASS1 | ENSLSDP00000014128 | ENSLSDP00000004246 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Argininosuccinate synthase. | 0.949 |
| ADSS2 | CPS1 | ENSLSDP00000014128 | ENSLSDP00000001898 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Carbamoyl-phosphate synthase [ammonia], mitochondrial. | 0.433 |
| ADSS2 | ENSLSDP00000001775 | ENSLSDP00000014128 | ENSLSDP00000001775 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | annotation not available | 0.552 |
| ASL | ADSS1 | ENSLSDP00000017484 | ENSLSDP00000024021 | Argininosuccinate lyase. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.552 |
| ASL | ADSS2 | ENSLSDP00000017484 | ENSLSDP00000014128 | Argininosuccinate lyase. | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.552 |
| ASL | ASS1 | ENSLSDP00000017484 | ENSLSDP00000004246 | Argininosuccinate lyase. | Argininosuccinate synthase. | 0.998 |
| ASL | CPS1 | ENSLSDP00000017484 | ENSLSDP00000001898 | Argininosuccinate lyase. | Carbamoyl-phosphate synthase [ammonia], mitochondrial. | 0.819 |
| ASL | NOS1 | ENSLSDP00000017484 | ENSLSDP00000018456 | Argininosuccinate lyase. | Nitric oxide synthase, brain. | 0.930 |
| ASL | NOS2 | ENSLSDP00000017484 | ENSLSDP00000019375 | Argininosuccinate lyase. | Nitric oxide synthase; Produces nitric oxide (NO); Belongs to the complex I LYR family. | 0.930 |
| ASL | NOS3 | ENSLSDP00000017484 | ENSLSDP00000018178 | Argininosuccinate lyase. | Nitric oxide synthase, endothelial. | 0.930 |
| ASL | OTC | ENSLSDP00000017484 | ENSLSDP00000009268 | Argininosuccinate lyase. | Ornithine carbamoyltransferase, mitochondrial; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. | 0.795 |