Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRDM12PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (351 aa)    
Predicted Functional Partners:
P2RX3
Purinergic receptor P2X 3.
      
 0.679
STK32A
Serine/threonine-protein kinase 32A; Belongs to the protein kinase superfamily.
      
 0.648
PHOX2B
Paired mesoderm homeobox protein 2B.
      
 0.626
EN1
Homeobox protein engrailed-like.
      
 0.565
SOX9
Transcription factor SOX-9.
    
 0.542
SOX10
Transcription factor SOX-10.
    
 0.542
OPRK1
Kappa-type opioid receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.520
HMGXB4
HMG domain-containing protein 4.
      
 0.519
DBX1
Homeobox protein DBX1.
   
  
 0.481
INSYN1
UPF0583 protein C15orf59.
      
 0.421
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (16%) [HD]