| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AUP1 | DERL2 | ENSLSDP00000018619 | ENSLSDP00000016196 | Ancient ubiquitous protein 1. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.564 |
| AUP1 | DERL3 | ENSLSDP00000018619 | ENSLSDP00000012397 | Ancient ubiquitous protein 1. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.564 |
| AUP1 | FAF2 | ENSLSDP00000018619 | ENSLSDP00000023193 | Ancient ubiquitous protein 1. | FAS-associated factor 2. | 0.837 |
| AUP1 | FAM8A1 | ENSLSDP00000018619 | ENSLSDP00000014755 | Ancient ubiquitous protein 1. | Protein FAM8A1. | 0.547 |
| AUP1 | OS9 | ENSLSDP00000018619 | ENSLSDP00000003454 | Ancient ubiquitous protein 1. | Protein OS-9. | 0.449 |
| AUP1 | SEL1L | ENSLSDP00000018619 | ENSLSDP00000004273 | Ancient ubiquitous protein 1. | Protein sel-1 1. | 0.976 |
| AUP1 | UBE2J1 | ENSLSDP00000018619 | ENSLSDP00000019058 | Ancient ubiquitous protein 1. | Ubiquitin-conjugating enzyme E2 J1. | 0.860 |
| DERL1 | DERL2 | ENSLSDP00000004408 | ENSLSDP00000016196 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.997 |
| DERL1 | DERL3 | ENSLSDP00000004408 | ENSLSDP00000012397 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.997 |
| DERL1 | EDEM1 | ENSLSDP00000004408 | ENSLSDP00000024223 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | 0.608 |
| DERL1 | FAF2 | ENSLSDP00000004408 | ENSLSDP00000023193 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | FAS-associated factor 2. | 0.950 |
| DERL1 | OS9 | ENSLSDP00000004408 | ENSLSDP00000003454 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Protein OS-9. | 0.920 |
| DERL1 | RNF185 | ENSLSDP00000004408 | ENSLSDP00000001036 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | E3 ubiquitin-protein ligase RNF185. | 0.966 |
| DERL1 | SEL1L | ENSLSDP00000004408 | ENSLSDP00000004273 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Protein sel-1 1. | 0.987 |
| DERL1 | UBE2J1 | ENSLSDP00000004408 | ENSLSDP00000019058 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Ubiquitin-conjugating enzyme E2 J1. | 0.669 |
| DERL2 | AUP1 | ENSLSDP00000016196 | ENSLSDP00000018619 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Ancient ubiquitous protein 1. | 0.564 |
| DERL2 | DERL1 | ENSLSDP00000016196 | ENSLSDP00000004408 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.997 |
| DERL2 | DERL3 | ENSLSDP00000016196 | ENSLSDP00000012397 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.901 |
| DERL2 | EDEM1 | ENSLSDP00000016196 | ENSLSDP00000024223 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | 0.672 |
| DERL2 | FAF2 | ENSLSDP00000016196 | ENSLSDP00000023193 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | FAS-associated factor 2. | 0.929 |