Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
FLRT2Leucine-rich repeat transmembrane protein FLRT2. (661 aa)    
Predicted Functional Partners:
FGF1
Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]
     
  0.759
FGF23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
     
  0.759
FGF4
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
  0.759
FGF3
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
  0.759
FGF5
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.745
DNAJC13
DnaJ subfamily C member 13.
      
 0.717
USP30
Ubiquitin carboxyl-terminal hydrolase.
      
 0.711
PTP4A1
Protein tyrosine phosphatase type IVA 1.
      
 0.695
FGFR4
Fibroblast growth factor receptor.
    
 0.639
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
  0.618
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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