Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)    
Predicted Functional Partners:
SMO
Smoothened; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.983
CSNK1A1
Casein kinase I isoform alpha; Belongs to the protein kinase superfamily.
     
 0.961
ARRB1
Beta-arrestin-1.
    
 0.908
CSNK1G2
Casein kinase I isoform gamma-2; Belongs to the protein kinase superfamily.
     
 0.901
CSNK1G1
Casein kinase I isoform gamma-1; Belongs to the protein kinase superfamily.
     
 0.901
CSNK1G3
Casein kinase I isoform gamma-3; Belongs to the protein kinase superfamily.
     
 0.901
CSNK1D
Casein kinase I isoform delta; Belongs to the protein kinase superfamily.
     
  0.900
CSNK1E
Casein kinase I isoform epsilon; Belongs to the protein kinase superfamily.
     
  0.900
GRK3
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
  
  
 
0.900
GNA11
Guanine nucleotide-binding protein subunit alpha-11.
    
 0.757
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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