Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110477989Cathepsin E-A; Belongs to the peptidase A1 family. (405 aa)    
Predicted Functional Partners:
AGT
Angiotensinogen; Belongs to the serpin family.
    
 0.773
ATP6AP2
Renin receptor.
   
 0.679
LOC110479107
Renin receptor.
   
 0.679
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.573
CTSH
Pro-cathepsin H; Belongs to the peptidase C1 family.
   
 0.552
CTSS
Cathepsin S; Belongs to the peptidase C1 family.
   
 0.543
CTSK
Cathepsin K; Belongs to the peptidase C1 family.
   
 0.543
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
   
 0.531
TC2N
Tandem C2 domains nuclear protein.
      
 0.528
CTSC
Dipeptidyl peptidase 1; Belongs to the peptidase C1 family.
   
 0.520
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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