Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
RNF40_1E3 ubiquitin protein ligase. (199 aa)    
Predicted Functional Partners:
WAC
WW domain-containing adapter protein with coiled-coil.
   
 0.858
CDC73
Parafibromin.
   
 0.821
LEO1
RNA polymerase-associated protein LEO1.
   
 0.807
PAF1
RNA polymerase II-associated factor 1.
    
 0.786
UBE2A
Ubiquitin-conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.779
UBE2B
Ubiquitin-conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.779
RNF40
E3 ubiquitin protein ligase.
 
      0.765
SETD2
Histone-lysine N-methyltransferase SETD2.
   
 
 0.763
CTR9
RNA polymerase-associated protein CTR9.
   
 0.736
UBA52
Ubiquitin-60S ribosomal protein L40.
    
 0.722
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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