Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)    
Predicted Functional Partners:
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.992
GRB2
Growth factor receptor-bound protein 2.
    
 0.983
SOS1
Son of sevenless 1.
   
 0.955
NTRK2
Tyrosine-protein kinase receptor.
    
 0.939
CRKL
Crk-like protein.
   
 0.932
FGFR4
Fibroblast growth factor receptor.
    
 0.925
FGFR1
Fibroblast growth factor receptor.
    
 0.898
FGFR2
Fibroblast growth factor receptor.
    
 0.898
NTRK3
Tyrosine-protein kinase receptor.
    
 0.868
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.853
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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