Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ITIH5Inter-alpha-trypsin inhibitor heavy chain H5. (1023 aa)    
Predicted Functional Partners:
HABP4
Intracellular hyaluronan-binding protein 4.
      
 0.601
COQ3
Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial.
   
 0.600
VCAN
Versican core protein.
      
 0.570
PPOX
Protoporphyrinogen oxidase.
   
 
 0.546
GMPS
GMP synthase [glutamine-hydrolyzing].
    
  0.489
NT5E
Snake venom 5'-nucleotidase; Belongs to the 5'-nucleotidase family.
     
  0.481
AP2A2
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
      
 0.438
SHROOM4
Protein Shroom4.
      
 0.436
OSBPL2
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.433
CEMIP
Cell migration-inducing and hyaluronan-binding protein.
      
 0.430
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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