STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZAP70Tyrosine-protein kinase. (602 aa)    
Predicted Functional Partners:
CD247
CD247 molecule.
   
 0.995
CD3E
T-cell surface glycoprotein CD3 epsilon chain.
   
 0.966
LCP2
Lymphocyte cytosolic protein 2.
   
 0.919
LOC110470410
T-cell surface glycoprotein CD3 gamma chain.
   
 0.899
GRAP2
GRB2 related adaptor protein 2.
   
 0.850
LCK
Tyrosine-protein kinase.
   
0.846
HCK
Tyrosine-protein kinase.
   
0.846
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.840
CBLB
E3 ubiquitin-protein ligase CBL-B.
    
 0.840
CD4
T-cell surface glycoprotein CD4.
   
 0.827
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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