Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZAP70Tyrosine-protein kinase. (602 aa)    
Predicted Functional Partners:
CD247
CD247 molecule.
   
 0.995
LCP2
Lymphocyte cytosolic protein 2.
   
 0.991
CD3E
T-cell surface glycoprotein CD3 epsilon chain.
   
 0.990
LOC110470410
T-cell surface glycoprotein CD3 gamma chain.
   
 0.983
LCK
Tyrosine-protein kinase.
   
 0.923
HCK
Tyrosine-protein kinase.
   
 0.923
CRK
Adapter molecule crk.
    
 0.895
ENSLSDP00000016760
annotation not available
   
 0.894
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.883
GRB2
Growth factor receptor-bound protein 2.
   
 0.876
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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