STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACSBG2Long-chain-fatty-acid--CoA ligase ACSBG2. (740 aa)    
Predicted Functional Partners:
FASN
Fatty acid synthase.
   
 0.926
CPT1B
Carnitine O-palmitoyltransferase 1, muscle isoform.
     
 0.911
CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform; Belongs to the carnitine/choline acetyltransferase family.
     
 0.911
PPT1
Palmitoyl-protein thioesterase 1.
   
 
 0.824
PPT2
Lysosomal thioesterase PPT2.
   
 
 0.823
MGLL
Monoglyceride lipase.
    
 0.815
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
    
  0.802
ACSL4
Long-chain-fatty-acid--CoA ligase 4.
  
0.752
ACSL3
Long-chain-fatty-acid--CoA ligase 3.
  
0.752
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.731
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.