Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
SAE1SUMO-activating enzyme subunit 1. (336 aa)    
Predicted Functional Partners:
UBA2
SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.
   
 0.998
UBE2I
SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.
  
 0.996
SUMO1
Small ubiquitin-related modifier 1.
   
 0.994
ENSLSDP00000000815
Small ubiquitin-related modifier 3-like.
   
 0.940
SUMO2
Small ubiquitin-related modifier.
   
 0.940
KCTD2
BTB/POZ domain-containing protein KCTD2.
  
 0.926
ENSLSDP00000000870
annotation not available
    
 0.767
UBE2M
NEDD8-conjugating enzyme Ubc12.
    
 0.767
UBE2F
NEDD8-conjugating enzyme UBE2F; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.767
RANGAP1
Ran GTPase-activating protein 1.
   
  
 0.733
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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