Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DMTF1Cyclin-D-binding Myb-like transcription factor 1. (767 aa)    
Predicted Functional Partners:
CCDC59
Thyroid transcription factor 1-associated protein 26.
   
 
  0.831
BTAF1
TATA-binding protein-associated factor 172.
   
 
 0.736
ARMC1
Armadillo repeat-containing protein 1.
      
 0.695
POLR1C
DNA-directed RNA polymerases I and III subunit RPAC1.
    
  0.627
TAF1
Transcription initiation factor TFIID subunit.
    
 
 0.625
POLR1E
DNA-directed RNA polymerase I subunit RPA49.
    
 0.607
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.599
SAMD12
Sterile alpha motif domain-containing protein 12.
      
 0.598
RUNDC3B
RUN domain-containing protein 3B.
      
 0.589
TDRD3
Tudor domain-containing protein 3.
      
 0.589
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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