close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESCO1N-acetyltransferase ESCO1. (851 aa)    
Predicted Functional Partners:
SMC3
Structural maintenance of chromosomes protein.
   
 0.985
PDS5A
Sister chromatid cohesion protein PDS5 A.
   
 0.936
PDS5B
Sister chromatid cohesion protein PDS5 B.
   
 0.919
SMC4
Structural maintenance of chromosomes protein.
   
 0.912
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.907
SMC1A
Structural maintenance of chromosomes protein 1A.
   
 0.897
SMC1B
Structural maintenance of chromosomes protein.
   
 0.897
SMC5
Structural maintenance of chromosomes protein 5.
   
 0.889
SMC2
Structural maintenance of chromosomes protein 2.
   
 0.874
SMC6
Structural maintenance of chromosomes protein 6.
   
 0.873
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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