Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
EML5Echinoderm microtubule-associated protein-like 5. (1977 aa)    
Predicted Functional Partners:
LOC110478774
E3 SUMO-protein ligase RanBP2.
   
 0.564
EPB41L4A
Band 4.1-like protein 4A.
      
 0.539
SLC6A7
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.539
MIS12
Protein MIS12.
     
 0.512
IFT140
Intraflagellar transport protein 140.
   
 0.501
NEK9
Serine/threonine-protein kinase Nek9.
   
  0.471
MAD2L1
Mitotic spindle assembly checkpoint protein MAD2A.
   
 0.464
CCNDBP1
Cyclin-D1-binding protein 1.
    
 0.455
AK9
Adenylate kinase 9.
    
  0.445
TOP3B
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
      
 0.435
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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