Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ROCK1Rho-associated protein kinase 1. (1366 aa)    
Predicted Functional Partners:
ROCK2
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
  
0.999
RHOA
Transforming protein RhoA.
    
 0.988
ENSLSDP00000018611
Protein phosphatase 1 regulatory subunit 12B-like.
   
 0.969
PPP1R12B
Protein phosphatase 1 regulatory subunit.
   
 0.969
PPP1R12A
Protein phosphatase 1 regulatory subunit.
   
 0.969
RND3
Rho-related GTP-binding protein RhoE.
    
 0.966
CASP3
Caspase-3; Belongs to the peptidase C14A family.
   
 0.952
LIMK2
LIM domain kinase 2.
    
0.949
LIMK1
LIM domain kinase 1.
    
0.949
SLC9A1
Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
    
 0.946
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
Server load: low (12%) [HD]