Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
METTL4Methyltransferase-like protein 4; Belongs to the MT-A70-like family. (481 aa)    
Predicted Functional Partners:
SMCHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1.
   
  
 0.877
METTL3
N6-adenosine-methyltransferase subunit; Belongs to the MT-A70-like family.
      
 0.874
METTL14
N6-adenosine-methyltransferase subunit METTL14; Belongs to the MT-A70-like family.
      
 0.874
N6AMT1
HemK methyltransferase family member 2.
      
 0.873
ALKBH4
Alpha-ketoglutarate-dependent dioxygenase alkB 4.
      
 0.789
METTL16
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...]
      
 0.681
PCIF1
Phosphorylated CTD-interacting factor 1.
      
 0.669
ALKBH1
Alkylated DNA repair protein alkB 1.
      
 0.665
WTAP
Pre-mRNA-splicing regulator WTAP.
      
 0.626
ALKBH5
RNA demethylase ALKBH5.
      
 0.593
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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