POT1 protein (Lonchura striata) - STRING interaction network

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Score

POT1

Protection of telomeres protein 1. (777 aa)

Predicted Functional Partners:

TERF2IP

0.998

LOC110476220

0.998

STN1

0.985

CTC1

0.984

TERT

0.948

TEN1

0.930

WRN

0.882

TERF2

0.865

DCLRE1B

0.859

RPA1

0.834

Your Current Organism:

Lonchura striata

NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTC1	LOC110476220	ENSLSDP00000008770	ENSLSDP00000022209	CST complex subunit CTC1.	Uncharacterized protein.	0.828
CTC1	POT1	ENSLSDP00000008770	ENSLSDP00000005340	CST complex subunit CTC1.	Protection of telomeres protein 1.	0.984
CTC1	RPA1	ENSLSDP00000008770	ENSLSDP00000018298	CST complex subunit CTC1.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.404
CTC1	STN1	ENSLSDP00000008770	ENSLSDP00000006763	CST complex subunit CTC1.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.999
CTC1	TEN1	ENSLSDP00000008770	ENSLSDP00000008443	CST complex subunit CTC1.	CST complex subunit TEN1.	0.999
CTC1	TERF2	ENSLSDP00000008770	ENSLSDP00000006014	CST complex subunit CTC1.	Telomeric repeat-binding factor 2.	0.756
CTC1	TERF2IP	ENSLSDP00000008770	ENSLSDP00000018833	CST complex subunit CTC1.	Telomeric repeat-binding factor 2-interacting protein 1.	0.820
CTC1	TERT	ENSLSDP00000008770	ENSLSDP00000024407	CST complex subunit CTC1.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.596
DCLRE1B	POT1	ENSLSDP00000010874	ENSLSDP00000005340	5' exonuclease Apollo.	Protection of telomeres protein 1.	0.859
DCLRE1B	TERF2	ENSLSDP00000010874	ENSLSDP00000006014	5' exonuclease Apollo.	Telomeric repeat-binding factor 2.	0.476
DCLRE1B	TERF2IP	ENSLSDP00000010874	ENSLSDP00000018833	5' exonuclease Apollo.	Telomeric repeat-binding factor 2-interacting protein 1.	0.960
DCLRE1B	WRN	ENSLSDP00000010874	ENSLSDP00000017027	5' exonuclease Apollo.	Werner syndrome ATP-dependent helicase.	0.445
LOC110476220	CTC1	ENSLSDP00000022209	ENSLSDP00000008770	Uncharacterized protein.	CST complex subunit CTC1.	0.828
LOC110476220	POT1	ENSLSDP00000022209	ENSLSDP00000005340	Uncharacterized protein.	Protection of telomeres protein 1.	0.998
LOC110476220	RPA1	ENSLSDP00000022209	ENSLSDP00000018298	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.533
LOC110476220	STN1	ENSLSDP00000022209	ENSLSDP00000006763	Uncharacterized protein.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.848
LOC110476220	TEN1	ENSLSDP00000022209	ENSLSDP00000008443	Uncharacterized protein.	CST complex subunit TEN1.	0.791
LOC110476220	TERF2	ENSLSDP00000022209	ENSLSDP00000006014	Uncharacterized protein.	Telomeric repeat-binding factor 2.	0.685
LOC110476220	TERF2IP	ENSLSDP00000022209	ENSLSDP00000018833	Uncharacterized protein.	Telomeric repeat-binding factor 2-interacting protein 1.	0.997
LOC110476220	TERT	ENSLSDP00000022209	ENSLSDP00000024407	Uncharacterized protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.907