SIGIRR protein (Lonchura striata) - STRING interaction network

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Score

SIGIRR

Single Ig IL-1-related receptor. (415 aa)

Predicted Functional Partners:

TOLLIP

0.690

UNC79

0.634

MYD88

0.580

TADA3

0.540

RUVBL1

0.533

RAG1

0.527

PIK3AP1

0.526

SARM1

0.507

PKP3

0.506

TRAF6

0.479

Your Current Organism:

Lonchura striata

NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MYD88	RAG1	ENSLSDP00000022508	ENSLSDP00000022270	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	0.712
MYD88	RUVBL1	ENSLSDP00000022508	ENSLSDP00000013670	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.469
MYD88	SARM1	ENSLSDP00000022508	ENSLSDP00000018425	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Sterile alpha and TIR motif-containing protein 1.	0.871
MYD88	SIGIRR	ENSLSDP00000022508	ENSLSDP00000005397	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Single Ig IL-1-related receptor.	0.580
MYD88	TOLLIP	ENSLSDP00000022508	ENSLSDP00000016670	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll-interacting protein.	0.842
MYD88	TRAF6	ENSLSDP00000022508	ENSLSDP00000022268	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
PIK3AP1	SARM1	ENSLSDP00000004694	ENSLSDP00000018425	Phosphoinositide 3-kinase adapter protein 1.	Sterile alpha and TIR motif-containing protein 1.	0.630
PIK3AP1	SIGIRR	ENSLSDP00000004694	ENSLSDP00000005397	Phosphoinositide 3-kinase adapter protein 1.	Single Ig IL-1-related receptor.	0.526
PKP3	SIGIRR	ENSLSDP00000005401	ENSLSDP00000005397	Plakophilin-3.	Single Ig IL-1-related receptor.	0.506
RAG1	MYD88	ENSLSDP00000022270	ENSLSDP00000022508	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.712
RAG1	SIGIRR	ENSLSDP00000022270	ENSLSDP00000005397	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]	Single Ig IL-1-related receptor.	0.527
RUVBL1	MYD88	ENSLSDP00000013670	ENSLSDP00000022508	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.469
RUVBL1	SIGIRR	ENSLSDP00000013670	ENSLSDP00000005397	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	Single Ig IL-1-related receptor.	0.533
SARM1	MYD88	ENSLSDP00000018425	ENSLSDP00000022508	Sterile alpha and TIR motif-containing protein 1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.871
SARM1	PIK3AP1	ENSLSDP00000018425	ENSLSDP00000004694	Sterile alpha and TIR motif-containing protein 1.	Phosphoinositide 3-kinase adapter protein 1.	0.630
SARM1	SIGIRR	ENSLSDP00000018425	ENSLSDP00000005397	Sterile alpha and TIR motif-containing protein 1.	Single Ig IL-1-related receptor.	0.507
SARM1	TRAF6	ENSLSDP00000018425	ENSLSDP00000022268	Sterile alpha and TIR motif-containing protein 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.728
SIGIRR	MYD88	ENSLSDP00000005397	ENSLSDP00000022508	Single Ig IL-1-related receptor.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.580
SIGIRR	PIK3AP1	ENSLSDP00000005397	ENSLSDP00000004694	Single Ig IL-1-related receptor.	Phosphoinositide 3-kinase adapter protein 1.	0.526
SIGIRR	PKP3	ENSLSDP00000005397	ENSLSDP00000005401	Single Ig IL-1-related receptor.	Plakophilin-3.	0.506