STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISCA1Iron-sulfur cluster assembly 1, mitochondrial. (129 aa)    
Predicted Functional Partners:
ISCA2
Iron-sulfur cluster assembly 2, mitochondrial.
  
 0.979
ISCU
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
  
  
 0.928
GLRX3
Glutaredoxin-3.
  
 0.875
NFS1
Cysteine desulfurase, mitochondrial.
  
 
 0.858
NFU1
NFU1 iron-sulfur cluster scaffold, mitochondrial.
  
 
 0.852
SCLY
Selenocysteine lyase.
  
 
 0.800
GLRX5
Glutaredoxin-related protein 5, mitochondrial.
   
 
 0.762
IBA57
Putative transferase CAF17, mitochondrial.
  
 
 0.761
FXN
Frataxin, mitochondrial.
   
 
 0.680
LIAS
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
  
 0.671
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.